ZytoVision introduces its new product line ZytoMation for fully automated FISH on Leica BONDTM Systems

ZytoVision introduces its new product line ZytoMation for fully automated FISH on Leica BONDTM Systems. FISH probes are designed for the detection of copy number alterations affecting the ERBB2 locus and for the detection of rearrangements affecting the ROS1 locus: ZytoMation ERBB2/CEN 17 Dual Color FISH Probe, and ZytoMation ROS1 Dual Color Break Apart FISH Probe.

ZytoMation® ERBB2/CEN 17 Dual Color FISH Probe

The ZytoMation® ERBB2/CEN 17 Dual Color FISH Probe is an automation probe designed for the detection of ERBB2 (a.k.a HER2) gene amplification frequently observed in solid malignant neoplasms e.g. breast cancer samples.

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ZytoMation® ROS1 Dual Color Break Apart FISH Probe

The ZytoMation® ROS1 Dual Color Break Apart FISH Probe is an automation probe designed to detect translocations involving the chromosomal region 6q22.1 harboring the ROS1 gene. Translocations affecting ROS1 have been detected in various tumors including non-small cell lung cancer (NSCLC). Administration of ROS1 kinase inhibitors may represent a very effective therapeutic strategy in NSCLC patients harboring activating ROS1 rearrangements.

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